CART Cells Assays
Vivia Biotech provides an assay with CART-cells on our collection of frozen hematological samples (AML or B-CLL). Customers decide the origin of the CART-cells, which can be provided by themselves or generated from our marrow-peripheral blood paired samples. We have experience in: in vitro assays with CART-cells (NKG2D or CD19) at different cell ratios and Time points with autologous or heterologous samples. The PharmaFlow platform can quantify the activity of CART- cells based on the number of live tumor cells remaining. In addition, our screening assays allow to measure specific tumor cell killing T-Cells based on Trogocytosis or doublet T Lymphocytes – Tumor Cells formation. We also offer the possibility to sort and perform a deep understanding of these specific subsets of CART-cells.
Tubeandbracket
Native Blook Cell Populations

CART-Cells

Cart Cells
Icubation T Cells
Plate Cart Cells

Hematological
Sample

Native Cell
Population

BsAbs Incubation
T-Cells Activation

Cells Retrieval &
FCM Readout

CART Cells Assays:
Native Environment

Hematological
Sample
Tubeandbracket
Native Cell Population
Native Blook Cell Populations
BsAbs Incubation T-Cells Activation
CART-Cells
Cart Cells
Icubation T Cells
Cells Retrieval & FCM Readout
Plate Cart Cells
CART Cells Assays:
Native Environment