Vivia Biotech ex vivo assays in discovery phase can reveal big differences in T Cell Engagers (TCEs) formats.
Vivia Biotech ex vivo assays in discovery phase can reveal big differences in T Cell Engagers (TCEs) formats. Isolated TCEs-activated T Cells against tumor cells over time and at different E:T ratios show different activity.
Different TCEs formats activate T cells with different killing activity.
Assay serves to select best TCE candidate
Comparison of three AML bispecific TCEs show different kinetics along time
We can differentiate distinct TCE formats aimed at the same target.
Assays can reveal critic differences in cellular death for each TCE format.
We can select the best TCE format still in discovery phase.