T Cell Engagers in Primary Patient Samples
We have high expertise in R&D of several TCE including IgG-like bispecific & trispecific antibodies, and other designs as DARTs, BiTEs, BiKEs, TriKEs, etc. using REAL PATIENT SAMPLES diagnosed with several hematologic malignancies and solid tumors
Vivia T Cell Engagers assays in a nutshell…
Target Expression
Cytokine Release
Target Selectivity of Activated T Cells
Quantitative T Cell Activation And Tumor Cell Killing
TCEs are Prodrugs Activating T Cells, Whose Killing Potency Correlate with Overall Survival
Activated T Cells as the Real Drug: Biomarker for Long-term Remission
Combination with Immune Checkpoint Inhibitors
Bell-Shaped Curves: Identify Dosing to Avoid Them
Proprietary Trogocytotic Biomarker Correlation with Activity: Suitable for Molecular Studies
