Functional Mapping of B-Cell Subsets
Comprehensive immunophenotyping of B cells provides detailed insight into the composition and activation state of B-cell compartments in autoimmune disease samples. Identifying and quantifying specific B-cell subsets is essential for understanding disease heterogeneity, monitoring immune dysregulation, and evaluating the impact of therapeutic agents on relevant cellular targets.
Vivia Biotech’s immunophenotyping assays enable detailed characterization of B-cell subsets in autoimmune disease samples. This includes naïve, transitional, memory, plasmablast, plasma cell, and double-negative populations, as well as activated B cells, defined by specific phenotypic profiles. The ability to resolve these subsets under native conditions provides essential information on immune dysregulation and supports both mechanistic evaluation and therapeutic targeting at the cellular level.